Differences in Levels of Human 1,3β-D-Glucan from Bronchoalveolar Lavage (BAL) Fluid in The Immunocompromised and Immunocompetent Groups Patients with Suspected Lung Cancer
نویسندگان
چکیده
Background: Invasive candidiasis occurs in immunocompromised individuals as an opportunistic infection patients with lung cancer. Although culture and histopathology remain the standard diagnosis of fungal infections, other tests are still needed to provide faster results. Human 1,3-β-D-Glucan (BDG) uses ELISA detect candidiasis. β D-Glucan level from BAL fluid is positive when cut-off p 130 pg / mL. This study aims determine differences levels 1,3β-D-Glucan Bronchoalveolar Lavage (BAL) between immunocompetent groups suspected cancer at RSU Dr. Saiful Anwar Malang.Method: A cross-sectional was conducted on 33 who had risk factors for invasive Hospital Malang.Result: significant (p = 0.009). In different tests, there a slight difference but it not statistically based age sex 0.632, 0.338, 0.472, 0.667).Conclusion: Patients have higher BDG due immunoparalysis. There were groups.
منابع مشابه
Bronchoalveolar Lavage Proteomics in Patients with Suspected Lung Cancer
Lung cancer configures as one of the deadliest types of cancer. The future implementation of early screening methods such as exhaled breath condensate analysis and low dose computed tomography (CT) as an alternative to current chest imaging based screening will lead to an increased burden on bronchoscopy units. New approaches for improvement of diagnosis in bronchoscopy units, regarding patient...
متن کاملthe study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولComplement factor H is elevated in bronchoalveolar lavage fluid and sputum from patients with lung cancer.
BACKGROUND Cytologic examination of specimens obtained from the respiratory tract is a lung cancer diagnostic procedure with high specificity but moderate sensitivity. The use of molecular biomarkers may enhance the sensitivity of cytologic examination in the detection of lung cancer. METHODS Complement factor H, a protein secreted by lung cancer cells, was quantified in a series of bronchoal...
متن کاملComparison of bronchoalveolar lavage and mini-bronchoalveolar lavage in the diagnosis of pneumonia in immunocompromised patients.
BACKGROUND Pneumonia is a major cause of morbidity and mortality in immunocompromised patients. Bronchoalveolar lavage (BAL) is commonly used to help diagnose and characterize pneumonia in these patients. Mini-BAL is a less-invasive, less-costly and less-cumbersome diagnostic tool than BAL. OBJECTIVES In this study, we compared the diagnostic value of BAL and mini-BAL in the evaluation of pne...
متن کاملMolecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer.
BACKGROUND Conventional cytologic analysis of sputum is an insensitive test for the diagnosis of non-small-cell lung cancer (NSCLC). We have recently demonstrated that polymerase chain reaction (PCR)-based molecular methods are more sensitive than cytologic analysis in diagnosing bladder cancer. In this study, we examined whether molecular assays could identify cancer cells in bronchoalveolar l...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Jurnal respirologi Indonesia
سال: 2022
ISSN: ['0853-7704', '2620-3162']
DOI: https://doi.org/10.36497/jri.v42i2.298